Terbinafine HCL Powder
Appearance: White Powder
CAS No.:78628-80-5
Function: Dermatological drug
Country of origin: China
Grade: Pharmaceutical grade
Application field: Medicine
Order lead time:7-15days
Payment method: T/T, paypal, western union
MOQ:1KG
Stock QTY:500KG
What’s Terbinafine HCL powder ?
Terbinafine HCL powder is a broad spectrum of acrylamide dermatological antifungal agent. It was developed by Novartis of Switzerland in the 1980s and first launched in the UK in 1991. It was approved as AN OTC drug by FDA in 1996 and launched in the United States in the same year. Currently, it is sold in more than 90 countries worldwide. It can specifically disrupt the late biodecomposition of fungal sterols, selectively inhibit the activity of squalene cycdrooxidase of fungi, and obstruct the epoxidation of squalene in the formation of fungal cell Chemicalbook membrane, thus reaching the effect of killing or inhibiting fungi. It is suitable for the treatment of skin candidiasis, such as tinea mantis, tinea pedis, tinea jocosa, tinea jocosa and tinea versicolor. In 2000, terbinafine hydrochloride entered the first OTC catalogue published by the state. The product belongs to antifungal drugs, it has a strong effect on superficial fungal infection, external use can cure most of the skin fungal disease.
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Product Specification
Product Name: | Terbinafine HCL powder | CAS NO.: | 78628-80-5 |
Molecular weight: | 327.89 | EINECS: | 616-640-4 |
Formula: | C21H26ClN | Melting point: | 204-208°C |
Function
It was reported that terbinafine hydrochloride 250mg was given orally, and the peak plasma concentration reached 0.97μg/ml within 2 hours after administration. The half-life of absorption is 0.8 hours, and the half-life of dispersion is 4.6 hours. Its biological application is slightly affected by feeding, but it is not used for dose adjustment. The drug binds to plasma proteins 99% of the time and disperses rapidly through the dermis and concentrates in the lipophilic cuticle. Terbinafine hydrochloride can also be dispersed in the skin and can be found in considerable concentrations in hair follicles, hair, and fatty skin due to Chemicalbook. Terbinafine hydrochloride can be put on deck during the final weeks of treatment. The biotransformed metabolites of this product have no antifungal activity and are mainly excreted from urine. It has a half-life of 17 hours, no accumulation in the body, and its steady-state plasma concentration is not affected by age. However, the elimination rate of terbinafine hydrochloride in patients with liver and kidney dysfunction can be reduced, resulting in lower blood concentration.
Application
Skin, hair and nail infections caused by trichophyllum (Trichophyllum albicans, Trichophyllum tendrii, Trichophyllum verrucatum, trichophyllum staphylococcus and trichophyllum purpurum, etc.), Canis microsporidium and trichophyllum floccus. 2. Various ringworm diseases (tinea physica, tinea jock, tinea mantinea, tinea capitis, etc.) and skin yeast infections caused by candida albicans, etc. 3. Onychomycosis caused by mold (onychomycosis).
Packaging & Delivery
Cargo weight | Packing | Shipping method | Lead-time |
5-50kg | Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum | International express | 7-10days |
100-200kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Air shipping | 7-10days |
Over 500kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Sea shipping | 20-45days |
Normally the packing is 25kg/drum; over 50kg we can ship by air; over 100kg we can ship by sea.
FAQ
1.Can we place order online?
Yes, we still have an online store, we just need your email to draft the order.
2. How to make payment and what is the payment term?
Payment can be done by T/T, Credit Card, Western Union, PayPal and more.
3. How about lead time?
Delivery time is about 3-5 days after payment made. But this need to be checked with sales person if there is stock.
4.Is there any discount?
Yes, some of the products is apply for discount, but it depends on the quantity.
5.Can you do OEM for me?
We accept OEM orders, just contact us and give us your design. We will offer you a reasonable price and make samples ASAP.
We can supply most of the active pharmaceutical ingredients (APIs) and Terbinafine HCL powder for customer, If you have any question or would like more information, be free to contact us via E-mail: info@haozbio.com
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