Rilpivirine Powder
Appearance: Off White Crystalline Powder
CAS No.: 500287-72-9
Function: Intelligence Enhancer and Pharmaceutical Intermediates
Country of origin: China
Grade: Pharmaceutical grade
Order lead time:7-15days
Payment method: T/T, paypal, western union
MOQ:25KG
Stock QTY:500KG
What’s Rilpivirine Powder?
Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcription inhibitor (NNRTI), which is used to treat HIV-1 infection.
Synonym
4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile;(E)-4-(4-(4-(2-cyanovinyl)-2,6-diMethylphenylaMino)pyriMidin-2-ylaMino)benzonitrile;4-[[4-[[4-[(E)-2-Cyanovinyl]-2,6-diMethylphenyl]aMino]pyriMidin-2-yl]aMino]benzoChemicalbooknitrile;4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-diMethylphenyl}aMino)pyriMidin-2-yl]aMino}benzonitrile;Rilpivirine(R278474;Rilpivirine(R278474,TMC278);Rilpivirine;4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
Product Specification
Product Name: | Rilpivirine Powder | CAS NO.: | 500287-72-9 |
Molecular weight: | 366.42 | Acidity Coefficient | 4.56±0.10(Predicted) |
Formula: | C22H18N6 | Melting point: | 245℃ |
Density: | 1.27 | Boilting point: | 634.1±65.0 °C(Predicted) |
Research in vitro
Rilpivirine exhibits antiviral activity against wild-type and selectively localizing single and dual hiv-1 mutants with an EC50 range of 0.1nMChemicalbook to 2nM. Rilpivirine inhibits viral replication, and first-generation NNRTIs fail to inhibit replication at concentrations and create high genetic barriers to impede development.
Research in vitro
After intravenous administration of Rilpivirine, elimination half-lives ranged from 4.4 hours in rats to 31 hours in dogs. The half-life of PEG 400 of Rilpivirine after oral administration ranged from 2.8 hours in rats to 39 hours in dogs.
Packaging & Delivery
Normally the packing is 25kg/drum; over 50kg we can ship by air; over 100kg we can ship by sea.
Cargo weight | Packing | Shipping method | Lead-time |
5-50kg | Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum | International express | 7-10days |
100-200kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Air shipping | 7-10days |
Over 500kg | 25kg/drum,use two layer PP bag,then into cardboard drum | Sea shipping | 20-45days |
FAQ
1.Can we place order online?
Yes, we still have an online store, we just need your email to draft the order.
2. How to make payment and what is the payment term?
Payment can be done by T/T, Credit Card, Western Union, PayPal and more.
3. How about lead time?
Delivery time is about 3-5 days after payment made. But this need to be checked with sales person if there is stock.
4.Is there any discount?
Yes, some of the products is apply for discount, but it depends on the quantity.
5.Can you do OEM for me?
We accept OEM orders, just contact us and give us your design. We will offer you a reasonable price and make samples ASAP.
We can supply the Rilpivirine for customer, If you have any question or would like more information, be free to contact us via E-mail: haozebio2014@gmail.com
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