Natamycin Powder

What’s Natamycin powder?

Natamycin, also known as picomycin or doxomycin, was first isolated from Streptomyces natalensis in 1955 and its activity is much better than that of sorbate. In June 1982, the United States FDA officially approved natamycin as a food preservative and classified it as GRAS. Natamycin is a kind of efficient inhibitor of mold, yeast and fungi, used to inhibit the mold Chemicalbook, yeast and fungi in food. It is very safe and reliable for human body, and does not affect the product flavor. Natamycin is widely used in cheese, meat products, pastries, juice and other food in the world. The product is refined from Streptomycesnatalensis by deep fermentation and multi-step extraction process. The preparation is composed of 50% natamycin and 50% lactose.

Synonym

NataMycin,A5283,Delvolan,Delvocid,Myprozine,Natacyn,Natafucin,PiMafucin,PiMafugin,A5263,CL12625,E235;Natamycin(FermentionProcess);(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-D-mChemicalbookannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylicacid;NATAMYCIN;PIMAFUCIN;PIMARICIN;PIMARICIN,STREPTOMYCESCHATTANOOGENSIS;antibiotica-5283

 

Product Specification

Product Name:	Natamycin Powder	CAS NO.:	7681-93-8
Molecular weight:	665.73	EINECS:	231-683-5
Formula:	C33H47NO13	Boilting point:	952℃
Density:	1.0 g/mL at 20 °C(lit.)	Specific rotation	D20 +278° (c = 1 in CH3COOH)

 

Function

Natamycin is a "polyene macrolide" fungal inhibitor produced by the fermentation of Streptomyces natalensis. It is also the only approved antifungal biological food preservative with high efficiency, broad spectrum, safety and natural. Natamycin relies on its lactone ring structure to interact with sterols on the fungal cell membrane to form sterols, thus destroying the structure of the plasma membrane. The hydrophilic part of macrolide forms water holes in the membrane, damaging the permeability of cell membrane, and causing the exudation of amino acids, electrolytes and other substances in the bacteria, resulting in the death of the bacteria. Natamycin, as a polyene antibiotic, acts by binding to sterols on fungal cell membranes. The cell surface of animals lacks sterols and is insensitive to polyene antimicrobials. Natamycin is therefore harmless to the human body and is difficult to be absorbed by the human digestive tract. No mutagenic, carcinogenic and sensitizing effects. Is a natural antifungal agent, with safe, efficient, natural, healthy characteristics.

 

Application

The European Union has approved natamycin for cheese and meat products, and the Netherlands has approved natamycin for apple and pear preservative. The United States FDA approved natamycin as a food preservative, allowing the use of natamycin on cheese. Countries in the Middle East allow natamycin to be used as a preservative in all food products. Brazil, Argentina and other Latin American countries allow the use of natamycin in cheese and meat products. Since 1997, the Ministry of Health has officially approved natamycin as a food preservative. It has been used for cheese, spiced meat products, smoked barbecue meat, fried meat, western Chemicalbook ham, meat sausage, fermented meat products, pastries, juice pulp and the surface of mold-prone food processing utensils. And added to fermented wines, mayonnaise, and salad dressings. The United States FDA approved the addition of 11ppm natamycin to feed to improve feed mildew situation. In 2000, Wyatt et al. studied the application of natamycin in feed. They put 191 potentially contaminated Aspergillus strains in the feed into a gradient plate containing natamycin, and found that the minimum lethal dose (MIC) of all Aspergillus strains was below 0.4g/L.

Packaging & Delivery

Normally the packing is 25kg/drum; over 50kg we can ship by air; over 100kg we can ship by sea.

Cargo weight	Packing	Shipping method	Lead-time
5-50kg	Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum	International express	7-10days
100-200kg	25kg/drum,use two layer PP bag,then into cardboard drum	Air shipping	7-10days
Over 500kg	25kg/drum,use two layer PP bag,then into cardboard drum	Sea shipping	20-45days

 

FAQ

1. Can I get some free sample?

Yes, we offer free sample of Natamycin powder to client but the shipping cost will be paid by client.

How to make payment and what is the payment term?

Payment can be done by T/T, Credit Card, Western Union, PayPal and more.

3. How does your factory make sure the product quality?

First of all, we have about 10years experience in this field, we already have a mature quality control procedure. Also we will final check before shipping to avoid any problem.

4. Can you do OEM for me?

We accept OEM orders, just contact us and send us your request. We will offer you a reasonable price and make samples ASAP.

5. How to get in touch with us?

You can chat with us by email, Skype and Whats-App or simply drop us an email, a phone call. All our contacts are shown in website.

 

 

We can supply most of the nootropic for customer, If you have any question or would like more information, be free to contact us via E-mail: info@haozbio.com

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