Glucosamine powder

Description

What’s Glucosamine?

Glucosamine powder, a natural amino monosaccharide, is essential for proteoglycan synthesis in human articular cartilage matrix. The molecular formula is C6H13NO5, with a molecular weight of 179.2. Formed by a hydroxyl group of glucose replaced by an amino group, easily soluble in water and hydrophilic solvents. Commonly present in microbial, animal-derived and bound polysaccharides as n-acetyl derivatives (such as chitin) or as n-sulfates and n-acetyl-3-O-lactate ethers (muramic acid).

Synonym

2-Amino-2-deoxyglucose;D-Glucose,2-amino-2-deoxy-;SHRIMP-DERIVEDGLUCOSAMINE;SYNTHETICGLUCOSAMINE;2-amino-2-deChemicalbookoxy-d-glucos;2-amino-2-deoxy-d-glucose;2-Amino-2-deoxy-beta-D-glucopyranose;2-Amino-2-deoxy-α-D-glucopyranose

Specification

Function

Glucosamine is an essential component for proteoglycan synthesis in cartilage matrix. Proteoglycans can make articular cartilage have the function of absorbing impact force by inhibiting the stretching force of collagen fibers. In the early stage of joint degenerative diseases, the biosynthesis of aggregated glucan is increased; In the later stages of the disease, the opposite is true. As a result, the cartilage becomes less elastic and develops the symptoms of arthritis. Amino monosaccharides can stimulate chondrocytes to produce glycoproteins with normal polymeric structure, inhibit some enzymes that can damage articular cartilage (such as collagenase), prevent the damage of corticosteroids and some non-steroidal anti-inflammatory drugs to chondrocytes, and reduce the release of endotoxin factors that damage cells. Exogenous glucosamine supplementation may play a beneficial role in the development of arthritis. In Vitro, When glucosamine was supplemented, chondroforming polymorpchic cells were able to synthesize more glucan aggregates. In animal models of arthritis, glucosamine also acts as an antioxidant, inhibiting the production of cell-damaging superoxide radicals. Through these pathways, glucosamine exerts a direct anti-inflammatory effect, which can relieve the painful symptoms of osteoarthritis, improve joint function, and prevent the progression of osteoarthritis.

Application

1.On immune regulation

Glucosamine participates in the metabolism of sugar in the body, widely exists in the body, and has a very close relationship with humans and animals. Glucosamine is involved in the protection of the body by combining with other substances such as galactose and glucuronic acid to form hyaluronic acid and keratin sulfuric acid, which have important biological activities of the body.

2.For osteoarthritis

Glucosamine is an important nutrient for the formation of human chondrocytes, a basic substance for the synthesis of aminoglycans, and a natural component of healthy articular cartilage. As we age, the lack of glucosamine in the body becomes more severe, and the articular cartilage degrades and wears away. Numerous medical studies in the United States, Europe and Japan have shown that glucosamine can help repair and maintain cartilage and stimulate the growth of chondrocytes.

3.Anti-oxidation, anti-aging

Some scholars have studied the antioxidant ability of chito-oligosaccharide and its protective effect on CCL4-induced liver injury in mice. The results show that chito-oligosaccharide has antioxidant ability and has a relatively obvious protective effect on CCL4-induced liver injury in mice, but cannot reduce the oxidative damage of DNA. In addition, the ameliorative effect of glucosamine on CCL4-induced liver injury in mice was studied. The results showed that glucosamine could increase the activities of major antioxidant enzymes in liver of experimental mice, while reducing the contents of AST, ALT and malondialdehyde (MDA), indicating that glucosamine had certain antioxidant capacity. However, CCl4 could not reduce the oxidative damage of DNA in mice. The antioxidant activity and the ability to activate immune responses of glucosamine have been studied by various methods in vitro and in vivo. The results showed that glucosamine could chelate Fe2+ well and protect lipid macromolecules from oxidative damage by hydroxyl radical. [3]

4.Anticorrosive and antibacterial aspects

Some scholars selected 21 kinds of common food spoilage bacteria as experimental strains, and studied the antibacterial effect of glucosamine hydrochloride on these 21 kinds of bacteria. The results showed that glucosamine had obvious antibacterial effect on 21 kinds of bacteria commonly found in food, and glucosamine hydrochloride had the most obvious antibacterial effect on bacteria. With the increase of glucosamine hydrochloride concentration, the bacteriostatic effect gradually became stronger.

Packaging & Delivery

Normally the packing is 25kg/drum; over 50kg we can ship by air; over 100kg we can ship by sea.

FAQ

1. Can I get some free sample?

Yes, we offer free sample of Glucosamine powder to client but the shipping cost will be paid by client.

2. How to make payment and what is the payment term?

Payment can be done by T/T, Credit Card, Western Union, PayPal and more.

3. How does your factory make sure the product quality?

First of all, we have about 10years experience in this field, we already have a mature quality control procedure. Also we will final check before shipping to avoid any problem.

4. Can you do OEM for me?

We accept OEM orders, just contact us and send us your request. We will offer you a reasonable price and make samples ASAP.

5. How to get in touch with us?

You can chat with us by email, Skype and Whats-App or simply drop us an email, a phone call. All our contacts are shown in website.

We can supply most of the pharmaceutical raw material for customer, if you have any question or would like more information, be free to contact us via E-mail: info@haozbio.com

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