Afatinib VS Ibrutinib

As we all know, lung cancer is a relatively difficult disease to treat, and ibrutinib and afatinib are one of the few drugs that can treat lung cancer. So what is the difference between afatinib and ibrutinib?

1. The scope of treatment
Afatinib is mainly used to treat EGFR mutation-positive advanced non-small cell lung cancer, and can also be used to treat EGFR WT (wild-type) lung cancer,
Ibrutinib can be used in the treatment of EGFR mutation-positive lung cancer and also in the treatment of HER2 mutation-positive lung cancer.

2. Dosage
The recommended oral dose of afatinib is 40mg/day according to the research, and the specific dose needs to be adjusted by the doctor according to the patient's tolerance.
According to the research, the recommended oral dose of ibrutinib is 600mg/day, but it should be taken after meals in order to improve the oral absorption rate.

3. Side effects
Common side effects of afatinib include diarrhea, oral ulcers, rash, hand-foot syndrome, etc., and serious side effects include interstitial lung disease, liver injury, etc.

Common side effects of ibrutinib include diarrhea, mouth sores, and rashes, and serious side effects include liver damage and lung disease.

All in all, when choosing an effective drug for the treatment of lung cancer, the appropriate dose and drug should be selected according to the patient's condition. Patients should be closely observed for side effects during administration.

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