Isotretinoin And Tretinoin, Which Is Better ?

May 26, 2023

Both isotretinoin and retinoic acid are derivatives of vitamin A, and they are widely used in the fields of cosmetics, health products, and medicine. The following is a comparison of their advantages and disadvantages and scope of application:

 

1. Mechanism of action:

Both isotretinoin and retinoic acid can stimulate cell growth and differentiation, promote cell regeneration and repair, and help improve dry skin, pigmentation, acne and other problems. But their mechanism of action is slightly different. Retinoic acid mainly acts by regulating the gene expression of receptors in the nucleus, while isotretinoin mainly acts by activating GPCR receptors on the cell membrane.

 

2. Scope of application:

Tretinoin is a more powerful drug, which is suitable for the treatment of severe acne, freckles, pigmentation and other skin problems.

Isotretinoin is relatively mild. In addition to being suitable for treating mild acne, skin aging, fine lines, and pigmentation, it can also be used to treat skin diseases such as keratosis and psoriasis.

 

3. Advantages and disadvantages:

Retinoic acid has a strong therapeutic effect and can quickly improve skin problems, but the side effects are also more obvious, such as dry skin, redness, irritation and so on.

The side effects of isotretinoin are relatively small, but its curative effect is also relatively weak, and long-term use is required to obtain significant results. In addition, isotretinoin works better with other drugs or cosmetics.

 

Generally speaking, both isotretinoin and retinoic acid have their scope of application and advantages and disadvantages, and should be used according to different skin problems and personal skin quality. It is recommended to use it under the guidance of a physician or professional, and pay attention to the correct dosage and frequency of use to avoid excessive skin irritation.

 

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