Chlorpheniramine Maleate

What’s Chlorpheniramine maleate?

Chlorpheniramine maleate is an organic compound with the chemical formula C20H23ClN2O4. It is mainly used as an antihistamine to treat rhinitis, skin and mucous membrane allergies, and relieve cold symptoms such as tearing, sneezing, and runny nose.

Synonym

1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethy-laminopropanebimaleate;1-Parachlorophenyl-1-(2-pyridyl)-3-dimethylaminopropanemaleate;2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-diChemicalbookmethyl-,(2Z)-2-butenedioate(1:1);2-Pyridinepropanamine,γ-(4-chlorophenyl)-N,N-dimethyl-,(Z)-2-butenedioate(1:1);Chlorophenamine;Chlorprophenpyridaminemaleate;Cloropiril;Histadur

Product Specification

Product Name:	Chlorpheniramine maleate	CAS NO.:	113-92-8
Molecular weight:	390.86	EINECS:	204-037-5
Formula:	C20H23ClN2O4	Density:	1.1984 (rough estimate)

Function

Chlorpheniramine is an H1 receptor antagonist, and its chemical structure belongs to the hydrocarbon amines. It mainly can competitively block the histamine H1 receptor on allergic target cells, so that histamine cannot bind to the H1 receptor, thereby inhibiting the allergic reaction caused by it. However, chlorpheniramine does not affect the metabolism of histamine, nor does it prevent the release of histamine in the body. Chlorpheniramine also has central nervous system inhibitory and anticholinergic effects, so after taking the drug, you may experience drowsiness, dry mouth, constipation, thickened sputum, and dry nasal mucosa. After long-term clinical practice, Chemicalbook believes that chlorpheniramine has a strong antihistamine effect, a small dosage, and few side effects. Chlorpheniramine has stronger antihistamine effect than diphenhydramine and promethazine, but has weaker central inhibitory effect and weaker anticholinergic effect. Since side effects such as drowsiness are mild, it is suitable for children and patients who need to work during the day. Chlorpheniramine also has the effect of reducing tracheal secretion and gastric acid secretion. Before the advent of new generation antihistamines, it was the most commonly used antihistamine in clinical practice.

Application

It is used for colds and allergic diseases of skin and mucous membranes. It is mainly used to treat urticaria, eczema, dermatitis, drug eruption, skin pruritus, neurodermatitis, insect bites, solar dermatitis. It can also be used for allergic dermatitis and vasomotor rhinitis. , drug and food allergies, etc. In addition to Chemicalbook's strong competitive blocking effect on histamine H1 receptors on allergy target cells, it not only plays an anti-allergic effect by antagonizing H1 receptors, but also has an anti-M cholinergic effect, so after taking the drug Symptoms such as dry mouth, constipation, thickened sputum, and dry nasal mucosa may occur.

Packaging & Delivery

Cargo weight	Packing	Shipping method	Lead-time
5-50kg	Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum	International express	7-10days
100-200kg	25kg/drum,use two layer PP bag,then into cardboard drum	Air shipping	7-10days
Over 500kg	25kg/drum,use two layer PP bag,then into cardboard drum	Sea shipping	20-45days

Normally the packing is 25kg/drum; over 50kg we can ship by air; over 100kg we can ship by sea.

FAQ

1. Can I get some free sample?

Yes, we can offer free sample of Chlorpheniramine maleate, but the shipping cost will be paid by client.

What is the payment term?

Payment can be done by T/T, Credit Card, Western Union, PayPal and more.

3. How does your factory make sure the product quality?

We have about 10years experience in this field, we already have a mature quality control procedure. Also we will do final check before shipping to avoid any problem.

4. Can you do OEM for me?

We accept OEM orders.

5. How to get in touch with us?

You can chat with us by email, Whats-App or simply drop us an email, a phone call. All our contacts are shown in website.

We can supply most of the raw pharmaceutical material for customer, If you have any questions or would like more information, be free to contact us via E-mail: info@haozbio.com

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