Obesity Has Become A Worldwide Problem,we Really Need To Solve This~

Two thirds of American adults are obese or overweight. According to the statistics of the World Health Organization, in 2008, 25.4% of Chinese people over 20 years old were overweight. Extra weight can increase the risk of hypertension, diabetes, hyperlipidemia, stroke, heart disease and osteoarthritis.

We need to find a way, then it comes out Lorcaserin.

Lorcaserin is a new drug for the treatment of obesity. It belongs to an oral effective selective serotonin 2C receptor agonist. Lorcaserin hydrochloride (belviqtm) was successfully developed by arena company in the United States and approved by FDA on June 27, 2012. It is used as an adjuvant treatment for overweight adult people with obesity or at least one weight related complication on the basis of low calorie diet and exercise. Clinical studies have shown that the drug can effectively reduce the weight of obese and overweight patients, improve obesity related metabolic indicators, and is well tolerated. The affinity of clocaseline for 5-HT2C is 100 times higher than that of 5-HT2B (risk of heart valve disease), with good safety. It is the first weight loss drug approved by FDA after 1999. After one year of treatment, the average weight loss ranged from 3% to 3.7%.

Lorcaserin is a selective serotonin agonist of serotonin 2C (5-HT2C) receptor, which is almost only distributed in the brain. The activation of this receptor can activate hunger and satiety pathways, including inducing proopiomelanogen and reducing appetite.

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