All About Brimonidine
What drug is Brimonidine?
Brimonidine is a receptor agonist, which is clinically used to reduce intraocular pressure in patients with open-angle glaucoma and ocular hypertension.
What are the uses of Brimonidine?
Brimonidine is mainly used to reduce intraocular pressure in patients with open-angle glaucoma and ocular hypertension.
What preparations and specifications are available for Brimonidine?
Brimonidine is a common clinical preparation, namely eye drops. The drug effects and adverse reactions may be different due to the different production process of the preparation from different manufacturers. Please consult your doctor for specific options.
Bromomonidine eye drops :5 mg /5 ml; 7.5 mg /5 ml; 10mg / 10ml; 15 mg /15 ml; 10 mg /5 ml; 20mg / 10ml; 30mg / 10ml.
Notice before medication
When is brimonidine prohibited?
People allergic to this product or any of its ingredients are not allowed. Contraindicated in patients who are being treated with monoamine oxidase inhibitors.
When should brimonidine be used with caution or avoided?
1,Use with caution in patients with serious cardiovascular disease.
2,Use with caution in patients with hepatic and renal insufficiency.
3,Patients with mental depression, cerebral or coronary artery dysfunction, Raynaud's sign, orthostatic hypotension, thromboangiitis obliterans should be used with caution.
4,It should be used by pregnant women only if the potential benefit outweighs the risk of harm to the fetus.
5,It is not clear whether brimonidine is excreted through milk, so nursing women should weigh the advantages and disadvantages and choose to stop breastfeeding or stop taking brimonidine. The safety and efficacy of pediatric medications have not been established.
People who have reacted seriously to iOP drugs (such as rutin and acetazolamide) should be used with caution.
6,Brimonidine and some drugs can interact and influence each other. If you are taking other medications, be sure to tell your doctor before taking brimonidine, and ask if it is available and how to use it.
There are adverse reactions to drugs. But don't be afraid of adverse reactions. You can read the drug label or consult your doctor to be prepared for any adverse reactions to brimonidine.
How do I take the medicine?
Bromomonil is prescribed as a prescription drug, which must be prescribed by a doctor according to the condition of the drug, and follow the doctor's advice, including the usage, dosage, medication time, etc. Do not use drugs according to drug instructions without authorization.
1. Drop into the conjunctival sac of the affected eye, 2 times a day, 1 drop a time. Patients with peak intraocular pressure in the afternoon or patients requiring additional intraocular pressure control can add 1 drop in the afternoon.
2. It can be used together with other intraocular pressure lowering drugs applied on the eye surface, but the medication interval should be more than 5 minutes.
Precautions during medication
1. Intraocular pressure should be monitored regularly for patients taking iOP drugs.
2. For patients wearing a soft contact lens, wait at least 15 minutes after dropping bromonidine.
3. As with all alpha-agonists, bromonidine can cause fatigue and/or burnout in some patients, so patients engaged in hazardous work should be warned of the possibility of impaired attention with bromonidine.
What about the adverse drug reactions?
There are adverse reactions to drugs. When adverse reactions are large, medical attention is required. The doctor will decide whether to continue or switch to another drug depending on the severity of the adverse effects.
When is immediate medical attention required?
Severe eye irritation, burning and tingling. Blurred vision.
Corneal staining and erosion. Syncope.
How should brimonidine be preserved?
Brimonidine should be shaded and stored at 15~25℃. Do not share this medication with anyone who has the same symptoms as you. Keep medicine away from children.
What are the possible adverse effects of brimonidine?
1,Dry mouth, burning and tingling sensation, headache, blurred vision, foreign body sensation, fatigue, conjunctival follicles, ocular allergy and ocular pruritus.
2,Corneal staining/erosion, photophobia, eyelid erythema, ocular pain/pain, dry eye, tearing, upper respiratory symptoms, eyelid edema, conjunctiva edema, dizziness, blepharitis, eye irritation, gastrointestinal symptoms, weakness, conjunctiva pallor, abnormal vision, and muscle pain.
3,Eyelid scab, conjunctival bleeding, abnormal taste, insomnia, increased conjunctival secretions, depression, hypertension, anxiety, palpitations, nasal dryness, and syncope. For other adverse reactions, please read the drug instructions carefully.
Which drugs interact with brimonidine?
1,Some drugs may interact with brimonidine, including prescription drugs, over-the-counter drugs, vaccines, vitamins, traditional Chinese medicine, etc. Consult your doctor before using these drugs with brimonidine.
2,The possibility of superposition or enhancement with central nervous system depressants (alcohol, barbiturates, opiates, tranquilizers or anesthetics) should be considered.
3,Care should also be taken when using β -antagonists (topical or systemic), antihypertensives and/or cardioside drugs simultaneously. · Bromonidine should be used with caution when patients are taking tricyclic antidepressants that affect circulating catecholamines metabolism or uptake.
Can brimonidine be used during pregnancy and lactation?
1,According to FDA standards, brimonidine is a safe grade C for pregnancy: adverse outcomes in animal reproductive studies, but no appropriate, controlled studies have been conducted in humans. These drugs should only be used if the benefits to the pregnant woman outweigh the risks to the fetus.
2,Pregnant women should consult a doctor before using; It is not known whether brimonidine can be secreted through milk, and lactating women should weigh the benefits and consult a physician before use.
How to use brimonidine rationally?
Drugs must be used rationally to avoid abuse. Prescription drugs should be prescribed by a doctor, and over-the-counter drugs should be read carefully.
Brimonidine is a prescription drug and must be prescribed by your doctor according to your condition. Self-medication may increase your risk of inappropriate drug use: waste of medication resources, delayed treatment, and serious adverse drug reactions.
