The Best Advantage Of Indapamide

The best advantage of indapamide

Indapamide is stable and effective in lowering blood pressure!

Highlight 1: Indapamide is rapidly and completely absorbed by mouth, with a bioavailability of 93%. With indapamide, there is no need to worry about the effect of food on the drug efficacy. Approximately 70% of indapamide is excreted through the kidney (7% of which is the original form) and 23% through the gastrointestinal tract.

Highlight 2: Indapamide belongs to a sulfa diuretic agent, which has prominent diuretic and calcium antagonistic effects. Its half-life is 14-18 hours, and the maximum antihypertensive effect is reached about 24 hours after a single oral dose. The maximum antihypertensive effect was reached about 8-12 weeks after repeated administration, and the effect was maintained for up to 8 weeks. The EFFECT IS NOT ONLY STRONG, BUT ALSO LONG-LASTING, WHICH IS A FEATURE OF INDapAMIDE COMPARED TO OTHER DRUGS THAT ARE MORE POTENT BUT HAVE a SHORTER DURATION.

Highlight 3: Indapamide can inhibit calcium influx, relax vascular smooth muscle, reduce vascular peripheral resistance and diuretic effect, and achieve antihypertensive effect. At the same time of antihypertensive effect, it has little or no effect on cardiac output, heart rate and rhythm, and is not easy to cause postural hypotension. Long-term medication rarely affects glomerular filtration rate or renal blood flow.

Highlight 4: This drug inhibited the distal renal tubule cortical dilution in the absorption of water and electrolytes, play a diuretic effect. In addition to the treatment of hypertension, it can also be used to treat water and sodium retention caused by congestive heart failure.

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