2-Phenylacetamide

1.Product name: 2-Phenylacetamide
2.Appearance:White powder
3.Molecular Formula:C8H9NO
4.Molecular Weight:135.16
5.CAS No.: 74610-55-2
6.Purity: 99%
7.Test Method: HPLC
8.Payment method: TT, Western Union,Paypal,Pingpong,Xtransfer,ect.
9.Shelf Life: 2 years

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Description

Product Introduction

2-Phenylacetamide is an organic substance with the chemical formula C8H9ON, 2-Phenylacetamide is white flaky crystal. 2-Phenylacetamide is soluble in hot water, ethanol, slightly soluble in cold water, ether and benzene.2-Phenylacetamide is used as an intermediate of Penicillin G and Phenobarbital and other drugs. Used in organic synthesis, it is the medium of penicillin G and the synthetic raw material of sedative drug phenobarbital.

Product Photo and action

2-Phenylacetamide

Product Specification

2-Phenylacetamide

Product Function

2-Phenylacetamide can be used as an intermediate in organic synthesis and pharmaceuticals, pesticides and spices. In the pharmaceutical industry it is the medium of penicillin G and the raw material of the sedative drug phenobarbital. Used as intermediates of penicillin and phenobarbital and other drugs. Also used in the preparation of phenylacetic acid, spices and pesticides to kill rodents raw material drugs

Pharmacology and Applications

2-Phenylacetamide is used in the pharmaceutical industry as a medium for penicillin G and as a raw material for the sedative drug phenobarbital.

Production method
Styrene, sulfur, liquid ammonia and water are put into autoclave and reacted at 165℃ and about 6.5MPa pressure, then heated and evaporated to drive off hydrogen sulfide gas, and then activated carbon is added to decolorize, cooled, crystallized, filtered and dried to get phenylacetamide. This method can be improved to pipeline continuous production, styrene and ammonium polysulfide liquid according to the volume ratio of 1:2 with the high-pressure pipeline, the reaction temperature of 200 ℃, reaction pressure of 6-7.8MPa, the reaction time of 1.5h. The reaction product of the post-processing process is similar to the autoclave intermittent method. Raw material consumption quota: styrene (99%) 1117kg/t, sulfur (98.5%) 716kg/t, liquid ammonia (99%) 539kg/t, Chemicalbook activated carbon 47kg/t. Another production method is to hydrolyze phenylacetonitrile (obtained by the reaction of benzyl chloride and sodium cyanide in aqueous dimethylamine) by heating in sulfuric acid or hydrochloric acid. Phenylacetonitrile is added to concentrated hydrochloric acid, dissolved with stirring, and reacted at 50°C for half an hour. Then slowly add water under cooling to precipitate crystals, cooled and filtered, washed with ice water to obtain the crude product. The crude product is washed with sodium carbonate solution, and then washed with ice water, after drying, the purer benzeneacetamide can be obtained. Raw material consumption quota: benzyl chloride (95%) 1190kg/t, sodium cyanide (95%) 527kg/t, dimethylamine (industrial) 20kg/t, sodium carbonate (industrial) 185kg/t, sulfuric acid (92.5%) 1760kg/t.

Product Application

2-Phenylacetamide